Aficamten treatment was associated with significant improvements in exercise capacity and symptoms compared with metoprolol in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

How Much Time Off Should You Take From Throwing After the Baseball Season
We discuss what the science shows about how much time off baseball pitchers should take from throwing in the offseason.